5 SIMPLE STATEMENTS ABOUT PKRRATING EXPLAINED

3B). R526 from the loop concerning αJ and αI anchors the C-terminal portion of the activation loop by forming a salt bridge with E458 at the base of αEF. Q459 stabilizes the HRD motif by a hydrogen bond to the most crucial chain carbonyl of R413. The tip in the activation segment is stabilized by a hydrogen bond among Y454 and E480 from αF. whi